1 Comments Share Best of luck! Since they moved to the Valley in 1988, the Arizona Cardinals have used a lot of starting quarterbacks — 30, in fact.While you may remember some of the details of what each signal caller did while wearing Cardinal red, we’re asking you to go a little further back in time.Can you name where each Cardinals starter went to school?No hints, just eight minutes on the clock! That’s your Trivia Tuesday challenge for this week, should you choose to accept it. Top Stories Derrick Hall satisfied with D-backs’ buying and selling Former Cardinals kicker Phil Dawson retires The 5: Takeaways from the Coyotes’ introduction of Alex Meruelo Grace expects Greinke trade to have emotional impact read more
US broadcast network CBS has launched a US$5.99 (€4.68) a month subscription streaming service.CBS All Access will offer subscribers thousands of episodes of CBS programming such as NCIS: New Orleans, plus access to live CBS programming in 14 major launch markets.The shows on offer will be a mix of current series, previous seasons and classics. New season shows will be offered a day after their linear broadcasts.It is now available from CBS.com and through an iOS and Android app.“CBS All Access is another key step in the Company’s long-standing strategy of monetising our local and national content in the ways that viewers want it,” said Leslie Moonves, president and CEO, CBS Corporation.“This new subscription service will deliver the most of CBS to our biggest fans while being additive to the overall ecosystem. Across the board, we continue to capitalise on technological advances that help consumers engage with our world-class programming, and we look forward to serving our viewers in this new and exciting way.” read more
“Chimney obstructions and blockages can lead to fumes and carbon monoxide entering rooms and it is therefore imperative that only suitably trained and competent people undertake this work.“Carbon monoxide and smoke alarms are vital in every home as they can provide time for people to escape but they should never be used as a substitute for the servicing of heating appliances and the sweeping of chimneys.“Landlords must ensure that all fires and stoves in properties they let are safe to use and the flues and chimneys serving them should be swept before each new tenancy of the property commences and regularly thereafter.”Mr Donaghy also reminded householders of the considerations they need to make before opening a fire in their home. “The public should be aware of the dangers of re-opening a fire that has been previously closed off,” he noted. “In order for this to be done safely all the necessary safety checks and precautions must be taken and any necessary approvals gained from the Building Control Department of Derry City and Strabane District Council.“It is also important to remember if you don’t own your own home you should gain your landlord’s permission.”Group Commander, Fergal Leonard, Prevention & Protection, NIFRS added:“From 1 December 2016 – 31 January 2017, Firefighters attended 167 accidental house fires, 11 of which were chimney fires.“At this festive time of year, people are spending more time at home and lighting their fires so they need be aware of the potential risks.“Chimney fires can be easily prevented by getting chimneys swept a number of times a year depending on the type of chimney and fuel you use, to ensure that they are safe and clean.“The cost of a chimney sweep is very small when compared to dealing with the damage and cost of repair after a chimney fire, not to mention the potential threat to life if the chimney fire were to spread to the rest of the property.“All households should have working smoke alarms fitted and they should be tested once a week.“Make sure you also have a fire escape plan and that everyone in your house knows the quickest means of escape.“In the event of a chimney fire call 999 immediately and ask for the Fire & Rescue Service.”It is also important to remember that to improve air quality, areas of Strabane, Castlederg and Newtownstewart have been designated as Smoke Control Areas and therefore only authorised smokeless fuels may be used in these areas.A list of Northern Ireland Association accredited Chimney Sweeps is available on the website https://niacs.co.uk/.Further information, including Chimney Fire Prevention Tips, is available from the NIFRS Community Information Bulletin at https://www.nifrs.org/wp-content/uploads/2013/05/Chimney-Fire-Prevention.pdf.HOUSEHOLDS URGED TO SWEEP THEIR CHIMNEYS FOR SANTA’S ARRIVAL was last modified: December 15th, 2017 by John2John2 Tags: WITH only a few days to go until Christmas Eve, Derry City and Strabane District Council and Northern Ireland Fire & Rescue Service are reminding local householders of the importance of having their chimneys regularly swept.As well as allowing Santa Claus to make a clean and safe entry into local homes this Christmas, regularly cleaning of chimneys can protect households from chimney fires and the risk of carbon monoxide poisoning, particularly in the winter months where heating appliances and fires are used more frequently.Head of Health and Community Wellbeing with Derry City and Strabane District Council, Seamus Donaghy, urged local householders to be aware of the need to keep their chimneys clean.“Having your chimney swept regularly not only removes a build-up of soot but also clears blockages such as nests and loose brickwork which may be obstructing a chimney,” he noted. ShareTweet HOUSEHOLDS URGED TO SWEEP THEIR CHIMNEYS FOR SANTA’S ARRIVAL read more
Mayor of Derry City and Strabane District Council, Councillor John Boyle, said the initiative was an ideal way to give young people hands on exposure to the logistics of event management.“I am delighted that Council are supporting the Youth Takeover initiative who are hosting this event in aid of Foyle Search and Rescue, my chosen charity for the year, and HURT who both do crucial work on the ground in the community,” he said.“The day has something for everyone with families catered for in the afternoon and older people able to take a trip into the 80s later that night with the film screenings and disco.“I am particularly pleased that our young people are running this day and they will gain valuable exposure and experience to the various elements of event management.” Fancy dress for the event is optional and limited tickets are still available, book now through the Nerve Centre website at https://nervecentre.ticketsolve.com/shows/873595323.Nerve Centre to host 80s themed youth takeover for local charities was last modified: October 30th, 2018 by John2John2 Tags: Charity HURTDerry and Strabane Councilfoyle search and rescueMayor John BoyleNerve Centre to host 80s themed youth takeover for local charitiesThe Lost BoysTHE NERVE CENTRE 80s themed day this Friday at The Nerve CentreTHE Nerve Centre’s Youth Takeover initiative will host an all-day music and movie event in aid of local charities Foyle Search and Rescue and HURT this Friday, November 2.‘Retrograde: Journey to the 80s’ promises a night jam packed with big hair, big tunes and the big screen and features a family friendly afternoon event and an over 18s film screening and disco in the evening. The project is funded by Derry City and Strabane District Council to give young people experience of event management and promotion.The classic ‘Who Framed Roger Rabbit’ will be screened in the Nerve Centre Cinema in the afternoon from 3 pm until 5.30 pm, admission is £3 with complimentary popcorn and sweets.Later in the day, 80s cult classics ‘The Lost Boys’ and ‘The Fly’ will be screened back to back alongside an exciting line-up of local DJs where admission is £6 and complimentary pizza is included.The Headline act at the on-site bar will be the fantastic Q Queen and Disco who will be wrapping it up with their signature sound and samples. ShareTweet read more
In This Issue. * Eurozone Retail Sales beat expectations! * Palladium nears 3 year high! * Canada prints Trade Surplus. * U.S. prints Trade Deficit. And Now. Today’s A Pfennig For Your Thoughts. Wheeler Pulls Out His “Diss The Currency Stick” Good Day! . And a Wonderful Wednesday to you! Pink Floyd’s Shine on you crazy diamond greeted me this morning, yes, all 7 parts, and 17+ minutes of music to start my day. I have a few 17+ minute songs on my IPod, including a couple by Neil Young and Crazy Horse. Now those will get you going in the morning! There are some mornings I need the extra push to get going, and then are mornings that I don’t. I prefer the mornings that I don’t need an extra push to get going. Not only for me, but for the currencies and metals! So, yesterday, was all about the currencies. Gold went nowhere, stocks took one for the team, but the currencies rallied VS the dollar. The U.S. stocks are down -1 to -2% depending on which exchange you follow, and the euro is up 1.28%, year to date, so it appears that the independent pricing mechanism of currencies from stocks, is back! Like Jack Bauer! Long time readers know that I disliked very much, every single day of that smartless Risk On, Risk Off dookie that the markets showed in our face since 2009, when the Fed embarked on their “signature bond buying program” and the risk assets were all thrown in a barrel to trade together. This morning, the currencies are a mixed bag of performance VS the dollar. The euro is down a few shekels this morning, while the Chinese renminbi saw a nice appreciation overnight. The New Zealand dollar / kiwi is getting taken to the woodshed this morning, while the Canadian dollar / loonie inches higher. So, like I said it’s a mixed bag of performance, and not the all-out currency rally like we saw yesterday. Gold is up a couple of bucks this morning, but the shining star of precious metals this morning is Palladium, which is trading near its highest price since 2011! So, guess who is the largest producer of Palladium? OK, no going to Google, to find out! Either you know it or don’t! The answer will be found at the bottom of the letter. Nah! Just kidding, Russia is the answer, so now you know why Palladium has a bee in its bonnet this morning. Once again, the traders appear to have been living under a rock, and just now came out to find that there’s a problem between Russia and Ukraine, for they are pointing to the Russia / Ukraine conflict as the reason their marking Palladium higher this morning. Well, yesterday, I talked glowingly about the Canadian Trade Surplus that was booked in Feb, and said that the experts were looking for that surplus to be added to in March. Unfortunately, that didn’t happen, and the March Trade Balance for Canada narrowed to just C$100 Million.. But, a surplus is a surplus, right? And the Canadian dollar / loonie has eked out a gain overnight on the surplus news. Speaking of narrowing but only on the deficit side of the ledger. The U.S. Trade Deficit narrowed March to $40.4 Billion down from the Feb deficit of $41.9 Billion. This narrowing was good, but didn’t even scratch the surface of retracing the deterioration of the Deficit in February. and should be about a .8% drag on 1st QTR GDP. UGH! And what was the first print of 1st QTR GDP? Well, it was a mere .1%, a rounding error from being negative folks. And. don’t forget, we’re adding up to 3% a year in “new found items for GDP”.. So, without this latest hedonic adjustment, GDP would have been negative in the 1st QTR. In addition to this drag on 1st QTR GDP isn’t enough. the reports from construction spending, and business inventories haven’t been what the experts on Wall Street were expecting, so the drag will be even greater.. So, the next revision of 1st QTR GDP will be negative, you can bet your sweet bippie! Well, that is, unless the Gov’t can find a few more “items to add to GDP” before the revision prints next month. OK. Long time readers know my feeling towards a country maintaining price stability through the strength of their currency. Many people through the years would like to argue with me about how having a strong currency had no effect on a country’s inflation. They are wrong of course, but to illustrate this, I always used Singapore as the model country that used currency strength to combat inflation rather than arbitrary central bank rate moves. Yesterday, though , I came across some research that really spelled it out for us. Russia, as you know, has been tied up in the problems involving Ukraine, and as a result their currency, the ruble, has lost about 11% since last October. And guess what? Russian inflation is accelerating too, posting a 7.3% level VS a year ago, and up from 6.9% in March! The main factor? The ruble weakness. Here in the U.S. the weak dollar has gone a long way toward causing inflation, but mostly in commodities, food, energy, houses, etc. Not wage inflation. That’s why I always tell people that a weak dollar causes a reduction in purchasing power, which is the same as losing price stability or high inflation. You can offset this loss of purchasing power by diversifying your investment portfolio with currencies and metals. My friends Dave and Addison over at the 5 Minute Forecast, touched on the inflation thing yesterday, with a quote from James Rickards. let’s go to the tape of the 5-Minute Forecast. “In a tug of war between evenly matched teams, not much happens at first,” said author Jim Rickards last summer at a symposium we held in Vancouver. The evenly matched teams are inflation and deflation. The Federal Reserve blows up its balance sheet north of $4 trillion. Inflation. But on the other side of the rope, too many people are still too scared to part with their money. Consumers don’t run up their credit cards, businesses don’t buy new plant and equipment. Deflation. While not much happens at first in a tug of war, eventually something starts to give way. And so it will go with inflation versus deflation. We get, say, $5,000 gold and $9-a-gallon gas… or $800 gold and gas below $2, the way it was in early 2009.” Someone sent me a note yesterday chastising me for talking inflation when deflation is all around us, according to him. I told him to go buy some beef, baseball tickets, a child’s tuition, some insurance, health and other, and then report back to me. Yesterday, I talked about the peripheral countries of the Eurozone, Spain & Italy, and how their PMI’s (manufacturing indexes) had beaten expectations. But that was somewhat wrong. the PMI’s were for Services non-manufacturing. They still beat the expectations, but I had them doing something they didn’t! UGH! So, I apologize for the faux pas. While I’m talking about the Eurozone, the region chalked up a good Retail Sales figure for March yesterday. Eurozone Retail Sales for March rose .3% VS Feb, and VS the expectations for a decline of -.2%! Apparently, the sales of” food, drink and tobacco” drove sales higher. I have no use for tobacco, but. I’m sure the sales of food and drink at the Butler house are sky high these days! But, Chuck, you don’t live in the Eurozone! Oh! You’re right, the BHI, won’t work here! HA! The Aussie dollar (A$) is down a bit this morning, after crossing .93-cents yesterday, and headed toward 93-cents. Australian Retail Sales for March didn’t rise as much as was expected by the so-called experts. March Aussie Retail Sales rose just .1% VS Feb, and 1st QTR Retail Sales hit +1.2%… Not shabby, but not as strong as I would have liked to see them. The last thing the A$ needs is for the calls to return calling for a rate cut. And reports like this will do that! But the Central Bank (RBA) meeting earlier this week is still too fresh in the minds of those that would make the calls for a rate cut. So, the A$ gets sold a bit. but not as badly as kiwi! The New Zealand dollar / kiwi is the worst performing currency overnight, and once again, it was verbal jawboning kiwi lower that led to this mess this morning. Reserve Bank of New Zealand (BNZ) Gov. Wheeler, brought back the “diss the currency stick” to swing at the lofty levels kiwi had reached in recent trading. Wheeler gave notice that the RBNZ is not happy with the current strength of kiwi, and if the strength of kiwi begins to hurt exports, it would raise the chances of intervention by the RBNZ. Let’s listen in to Wheeler. “It would become more opportune for the Reserve Bank to intervene in the currency market to sell New Zealand dollars if the kiwi fails to respond to worsening fundamentals.” So, kiwi got whacked! And Wheeler didn’t have to do anything, especially intervene, except let his inner desire to diss the currency come out in words. Do you know the music of Al Stewart? I’ve always been a fan. The lyrics to his songs are so magical and tell great stories. And his music weaves in and out of soft rock, jazz, and other stuff.. I’m listening to his song: Time Passages right now, let’s visit some of his magical lyrics. “Well I’m not the kind to live in the past. The years run too short and the days too fast. The things you lean on are the things that don’t last. Well it’s just now and then my line gets cast into these Time Passages”. Well. did you see that China’s internet giant, Alibaba, is coming to the U.S. in the form of an IPO? I find this to be interesting in the long line of things that China has been doing to wrestle the reserve currency status from the U.S. I’m not sure how it all fits in, but I’m sure when we look back on this in a few years, it will all come to us. Like the Blind man said who spit into the wind. It’s all coming back to me now. I had several people send me the link to a story in the NY Times yesterday that talked about the court case involving people / investors suing the bullion banks (JP Morgan, HSBC, and more) over Gold price suppression. I told the boys and girls on the desk that nothing will come of this, for the architects of the Gold price suppression are above the Bullion Banks. Former Treasury Executive, Paul Craig Roberts, told us a few months ago, what’s and who is behind the 8-ball here. But, I have to give these investors some credit for getting it to court! My long-time friend, and former mentor, Ed Bonawitz, asked me, “if precious metals are rigged, why invest in them.” Ahhh master, your grasshopper has learned well how to answer the master’s fuzzy questions. Because they won’t be rigged forever.. And the rigging just gives us all cheap levels to buy! The U.S. Data Cupboard is still searching for some meat, but in the meantime, we’ll see some data on Mortgage applications from last week (was there bad weather last week? HA!), And Consumer Credit, which has really gone berserk in recent months to the upside, showing us once again, that no one ever learns a lesson. And like I told you last week, lessons learned should be like bridges burned, you only need to cross them but once. – Dan Fogelberg. Speaking of not learning lessons. I saw a story go across the screen yesterday, and I read it out loud to the desk so they could pass judgment too.. Here’s the story title from Bloomberg: ” Italian Gov’t Bond yields fall below 3% for the first time. ever. Sure, Italy has taken steps to improve their balance sheet, but there’s a ton more work to do here, and the markets are acting as if all the work has been done already. I don’t like this. For What It’s Worth. Ok.. I found this on Bloomberg and it’s an article about a dinner conversation between former Fed Chairman, Big Ben Bernanke, and David Einhorn, manager of the $10 Billion Greenlight Capital Inc. It’s quite long, so I had to cut snippets from the article to fit it in here. But here are a couple of the things discussed at this dinner meeting. “”I got to ask him all these questions that had been on my mind for a long time,” Einhorn said in an interview, it was sort of frightening because the answers were not better than I thought they would be.” Einhorn criticized Bernanke for saying he was 100 percent certain there would be no hyperinflation and that it generally occurs after a war. “Not that I think there will be hyperinflation, but how do you get to 100 percent certainty about anything?” Einhorn said. “Why can’t you be 99 percent certain?” Bernanke responded “you are wrong” to a question about the diminishing returns of having interest rates at zero, according to the hedge-fund manager. The ex-Fed chief’s explanation, Einhorn said, was that raising interest rates to benefit savers wouldn’t be the right move for the economy because it would require borrowers to pay more for capital.” Chuck again. Man, would I like to have been at that dinner table! And no I wouldn’t be mean, or snarky, I would just like to listen to the answers, and look in his eyes to see if he’s giving the company line, or his true answer. To recap. The currency rally from Tuesday, had no legs left to run on overnight, and this morning. The currencies are a mixed bag of results, but the metals are stronger this morning. The traders for Palladium finally came out from under the rocks they were living under to find that Russia might be tied up in a conflict for some time, thus slowing the production of Palladium, which has led to Palladium nearing a 3-year high this morning. The U.S. Trade Deficit narrowed in March, but failed to retrace the deterioration of the Deficit that occurred in Feb. And Chuck talks forever about Al Stewart. Currencies today 5/7/14. American Style: A$ .9340, kiwi .8680, C$ .9190, euro 1.3930, sterling 1.6965, Swiss $1.1435, . European Style: rand 10.5190, krone 5.9100, SEK 6.4975, forint 219.75, zloty 3.0165, koruna 19.6815, RUB 35.49, yen 101.65, sing 1.2490, HKD 7.7515, INR 60.09, China 6.1542, pesos 13.03, BRL 2.2285, Dollar Index 79.13, Oil $100.35, 10-year 2.58%, Silver $19.65, Platinum $1,450.94, Palladium $815.75, and Gold. $1.310.62 That’s it for today. It was a very nice night at Senior Night at Alex’s Water Polo Game last night, and he scored a goal in his last home pool game, as the team won its last regular season game before the playoffs begin this week. Have you been following all the vehicle recalls that get announced on what seems to be every day now? Crazy! Cardinals forget to hit again last night, and waste a great outing by their young pitcher. I got to watch the first two hours of 24 yesterday. WOW! Next week it will begin with, “previously on 24”. I love it! The Young Rascals are singing: Groovin’ right now. Now that’s an expression that doesn’t get used any longer. So, unless you were around for the 60’s, that probably doesn’t make much sense to you! Well, the NFL Draft is tomorrow night.. The Rams get two of the first 13 picks. They had better use them wisely! And now, I will send you off to make this a Wonderful Wednesday! Bye! Chuck Butler President EverBank World Markets read more
Recommended Links The next big bankruptcy Here in the USA, the Dow crashed 871 points in just two days. Now, another major European country is voting to leave the EU. If it leaves (and it surely will) markets could plummet again… Only this time, it’ll be much, much worse. Click here to learn more. V-Day helped organize Italians frustrated by their political system. It gave birth to the Five Star Movement, Italy’s new populist political party. Grillo’s Five Star Movement—or M5S, as it’s known by its Italian acronym—is anti-globalist, anti-euro, and anti-establishment. It doesn’t neatly fall into the left/right political paradigm. According to the latest polls, M5S is now the most popular party in Italy. It won mayoral elections in Rome and Turin earlier this year. M5S is riding a wave of populist anger at entrenched political elites over economic stagnation. Italy has had virtually no productive growth since it joined the euro in 1999. M5S blames Italy’s chronic lack of growth on the euro. A large plurality of Italians agree. M5S has promised to hold a vote to leave the euro and return to Italy’s old currency, the lira, as soon as they’re in power. Under these circumstances, it would probably pass. Meanwhile, the current pro-EU Italian government of Matteo Renzi is holding a referendum on changing the Italian constitution later this year. This referendum is on limiting the powers of the Italian senate, which is seen as a source of political gridlock. Opponents say it could open the door to another strongman like Benito Mussolini. More importantly, it’s effectively a vote of confidence in the current pro-EU government. Voting against it is a way for the average Italian to give the finger to the EU bureaucrats in Brussels. Renzi has promised to resign if it fails. If the referendum fails, M5S—the anti-euro populist party—will almost certainly come to power…and a pathway to the dissolution of the euro will be opened. That’s why Italy’s upcoming constitutional referendum is so significant. It’s why I’ve spent weeks on the ground in Italy to get the scoop on this explosive story that almost nobody else is talking about. Editor’s note: To learn more about this story, Nick and his team put together an exclusive video that explains exactly what you need to do to profit from Europe’s coming crisis. In short, just two months from now, a monumental event will take place in the heart of Europe. If this event goes the way we expect, it could unleash a crisis five times more destructive than the “Brexit.” It could even mark the end of Europe as we know it. To learn more about this upcoming event, watch this FREE presentation. – Do you have $4 to invest? As of September 1, you can buy shares in Silicon Valley using “Plan B.” It’s a new way of investing in startup ideas, like Airbnb… Dropbox… or Uber – no matter what your income. Click here for details. — Editor’s note: Over the next few days, you’ll notice a familiar theme running in the Dispatch. It’s one of the most important topics in the world today…and it has major implications for every investor going forward. As you’ll see, Europe is on the brink of an epic collapse…and it’s presenting once-in-a-lifetime profit opportunities for those who know how to play it. Today, to kick this miniseries off, we have a special essay from Crisis Investing editor Nick Giambruno, who just got back from Italy to uncover a part of this story that no one is talking about today… By Nick Giambruno, editor, Crisis Investing The stage is set for the collapse of the world’s largest economy—the European Union. The trigger: Italy’s exit from the euro currency. The Financial Times recently put it this way: An Italian exit from the single currency would trigger the total collapse of the eurozone within a very short period. It would probably lead to the most violent economic shock in history, dwarfing the Lehman Brothers bankruptcy in 2008 and the 1929 Wall Street crash. If the Financial Times is even partially right, it means we’re looking at a possible stock market crash of historic proportions. It could devastate anyone with a brokerage account. But it could also present enormous opportunities to profit. Here’s how it could happen… What started out as a joke has become Italy’s most popular political party. In 2007, Beppe Grillo, an Italian actor and comedian, launched Vaffanculo Day (“vaffanculo” is Italian for “f*** off”). Grillo and his followers used V-Day to bluntly express their displeasure over establishment Italian politicians, using imagery from the movie V for Vendetta. read more
This week, ProPublica and Time Magazine released a report on More Than Me, a charity founded by American Katie Meyler to provide an education to Liberian girls and protect them from sexual exploitation. In 2012 the charity won the $1 million American Giving Award, sponsored by JPMorgan Chase.In 2013, MTM started its own school. Over the years, it raised some $8 million, with a nearly $600,000 contribution from the U.S. government.The press praised the group, particularly as the Ebola outbreak unfolded in 2014. NPR highlighted the charity’s work in a post here. But according to the report, Macintosh Johnson, a Liberian identified as a “co-founder” of MTM, raped a number of girls from the academy. Ten girls pressed charges. An MTM document, labeled “confidential,” said a student had identified 30 victims.Journalists Finlay Young and Kathleen Flynn spent nearly a year digging into the story to produce a 13,000-word story and a documentary film. Young interviewed 80 individuals, including two girls who had testified against Johnson.”It allowed us the time really to delve deep and to treat the victims in this case in exactly the same way as we would treat them in a story in any country,” says Young.We talked with Young about his work on the investigation. This interview has been edited for length. You were in Liberia during the time that More Than Me was getting established in Liberia. What was the impression you had of the organization and of Katie Meyler then?Meyler is someone who [is] committing everything she’s got, and it’s an altruistic endeavor. I think that’s fair to say. It’s possible to make a lot of money working in international aid, and that wasn’t Katie Meyler. Even before any of this stuff came to light, there was a sense of vulnerability in More Than Me, because you had a lot of idealism, which is obviously a great thing. But you also had a lot of inexperience throughout the organization. You had a lot of people trying their best, but perhaps they weren’t prepared for the complexity of what they were trying to do. I think it’s fair to say based on our reporting that Meyler didn’t necessarily understand the risks of what to her seemed like a simple endeavor of getting kids off the street and into school. Liberia is complicated and bad things happened, and then bad things became worse things. The alleged abuse at the school first came out in 2014, just before Ebola hit. How did More Than Me leaders respond when they discovered you were investigating what had happened? There’s a symbiotic relationship between charities and journalists. Charities can provide journalists with easy stories. But it very much changes that dynamic when the journalists look at the charity as a possible agent in bad stuff happening, and that’s what happened in this story. The response to two journalists looking into what had taken place was astonishing. We weren’t talking about a huge massive charity. We were talking about a small charity, but also a charity whose founder had a lot of experience with media and was able to leverage the media to tell stories to raise an awful lot of money. First of all, Meyler wouldn’t go on the record, which is understandable in some ways. But once a PR company based in Manhattan was involved, it got much more serious. I don’t know the decision-making behind the scenes, but vulnerable sources of ours, people we had interviewed in confidence in Liberia, ended up being questioned by the charity. Basically, what do you think of More Than Me? What did the journalist ask you? Would you like to take your information back if you could? And the PR company made accusations of unethical conduct, suggested that we hadn’t been clear who we are, that we didn’t have informed consent — the kind of stuff that, as a journalist, is the worst thing you can be accused of. That was hard in some ways to understand, because it meant that the story had to get longer. But in a way it made sense, because it was an organization that put itself in the center of the story throughout. And then in a negative story, they ended up putting themselves in the center of the story again, which was challenging for us, because we were so determined that the center of the story would be the experience of these incredibly brave young women [who came forward to tell their stories].You mentioned you wanted to investigate and tell the story in the same way journalists would in other countries. Was that process harder in Liberia, especially given the local support for More Than Me?A lot of our facts, in terms of timelines and who was where and everything else, came from social media. Many of the actors involved were very active in social media, so it was very modern in that way. But that was mixed up with an awful lot of pursuing strange leads in a taxi in the really hot weather, and waiting and chasing down these sources. There’s an assumption very often that in a place like Liberia, there won’t be any documents, there won’t be rigorous transcripts, there won’t be all these things you need to report. That’s not always true. You can say “It’s Liberia and it’s harder,” but the traditional elements of corroboration and following up are there. It’s just a slightly separate context. Editor’s note: In the wake of the investigative story being published, More than Me issued this statement:”We are deeply, profoundly sorry. To all the girls who were raped by MacIntosh Johnson in 2014 and before: we failed you. We gave Johnson power that he exploited to abuse children and staff failed to report the abuse to our leadership immediately. Our leadership should have recognized the signs earlier and we have and will continue to employ training and awareness programs so we do not miss this again….”We acknowledge the enormous complexity of being responsible for the care of children and that previously we were naïve to believe that providing education alone is enough to protect these girls from the abuses they may face …. An independent audit completed this summer called for the implementation of a range of changes including survivor-centered protocols, additional resources to ensure efficient reporting, broad application of safety standards to all of our public schools and organizational culture change and we continue to be firmly committed to further bolstering our safeguarding policies. As we work to correct past failures, we welcome the Ministry of Education to the Academy at any time for a complete inspection.”We regret that coverage in ProPublica and Time presented a one-sided view of our overall work and achievements, often quoting out of context or minimizing our institutional development and impact over the past four years.”ProPublic and Time have responded: “The organization did not identify any inaccuracies.” In an update, they also report that “Katie Meyler … temporarily stepped down from her position as the American charity’s chief executive officer pending the results of a Liberian panel’s review” of the investigative report. Copyright 2018 NPR. To see more, visit http://www.npr.org/. read more
A hashtag called #ThisIsMyHustle started trending in Nigeria in mid-March after Sadiq Abubakar, 30, a small-business owner from Abuja, organized a Twitter chat for his entrepreneur friends.”I said, ‘Let’s do a hashtag and let the world know what we do,’ ” he says. “Young Nigerians are very determined to succeed. What we hear about young Nigerian people is that we are lazy. But we are hardworking. We want to make it.”He was just expecting a couple of dozen people in his network to tweet — but within an hour, he says, the hashtag went viral in Nigeria, prompting thousands of responses. People started sharing posts that promoted not just their side hustles but also their main gigs, from coding to baking to making art.The hashtag has garnered the praise of Bashir Ahmad, the personal assistant of President Muhammadu Buhari, who wrote on Twitter: “Spent over an hour reading every tweet under #ThisIsMyHustle hashtag, every single tweet made me happy genuinely … I am super proud of you all.”Jobs are hard to come by in Nigeria, says Abubakar, so many people have to “hustle” to earn money — starting their own businesses or finding side jobs to supplement their main income. According to Nigeria’s National Bureau of Statistics, the unemployment rate in the country was at 23 percent as of the third quarter of 2018.”Young people finish school and then are not able to find a job,” he says. “So they start selling anything they can to make an income. They don’t want to burden their parents.”Abubakar knows what that’s like. He graduated from the University of Leeds in the U.K. in 2013 with an MBA but says he has not been able to find a white-collar job in his homeland.So he decided to start his own company. In 2014, he launched Beta Business Forum, which helps small-business owners with marketing and sales. He’s also earning money as a real estate agent and a farmer. And he plants cash crops like sorghum and corn.”This hashtag actually opened my eyes. I had no idea that there were this many Nigerians hustling out there,” he adds.A number of the tweets are about agriculture, which has been hard to sell to youth in sub-Saharan Africa as a viable career.”Young people [in Africa] face particular barriers that often lead to skepticism about farming as a viable future,” wrote Kanayo F. Nwanze, former president of the International Fund for Agricultural Development, in 2018. “Youth and other marginalized groups do not see farming as a business, as an economic enterprise.”Sadiq Muhammed Kabir, 24, runs his own import-export business selling ginger root in Kaduna. He was proud to share photos of his work on #ThisIsMyHustle. “Most young people in my country don’t really see [farming] as something good,” he says. “They forget that farming is very, very lucrative.”Abubakar says he has received a lot of positive feedback over the last few days from business owners who have been tweeting on the hashtag. “They’re telling me that they have been getting more clients,” he says.Kabir says that his post has brought in some business too. After he posted his tweet, he says, “my life has never been the same. I got buyers around the world, like Canada, Dubai, even North America.”As with many other hashtag campaigns, some people on Twitter had hilarious responses to the tweets.Esther Ngumbi is a researcher at the University of Illinois and a New Voices fellow at the Aspen Institute. Copyright 2019 NPR. To see more, visit https://www.npr.org. read more
Disabled campaigners have called on parliament to press for new laws that would allow candidates to stand jointly for election as job-share MPs, after a judge threw out a legal case brought by two members of the Green party.Disabled activists believe that allowing more than one person to job-share as an MP would increase the number of disabled people and women represented in parliament.Both the Greens and the Liberal Democrats have endorsed the idea, and the Lib Dems included it in their general election manifesto.But the high court this week rejected an application by Green party activists Clare Phipps and Sarah Cope, who argued that they should have been allowed to stand together for election to the Basingstoke seat at May’s general election.The court said the law was clear that only single candidates could stand for election as an MP.Neither Phipps nor Cope would be able to serve as a full-time MP because Cope is the main carer for two young children, and Phipps has an impairment that prevents her working full-time. Deborah King, co-founder of Disability Politics UK, which campaigns for MPs to be allowed to job-share, said she was “disappointed” by the court’s ruling, although the judge had recognised the “important social and political issues raised by the case”.She said: “Parliament now has to consider the issue of job-sharing for MPs properly.”King plans to write to the political parties and the Commons speaker John Bercow to ask for his inquiry into parliamentary representation to be re-opened, so that it can hear evidence on “how job-sharing for MPs would work in practice”.Bercow’s Speaker’s Conference reported five years ago on how to increase the number of disabled, female and minority ethnic MPs, but did not back the idea of job-share MPs.King said: “The last conference of MPs decided amongst themselves behind closed doors that it was not possible. We need objective, evidence-based policy-making, rather than guesswork from our MPs.”Dr Sarah Wollaston, the Conservative MP for Totnes, who has worked as a job-sharing GP, has said she would be willing to give evidence to such a conference.King said the 2015 Conservative manifesto included pledges to increase the number of female MPs, and to remove the barriers to workforce participation faced by women and disabled people.She said: “Enabling MPs to work part-time would be a removal of a barrier to work for many people.“We need politicians from all parties to take the steps needed to bring the Commons into the 21st century.”Adam Lotun (pictured), a disabled activist who was rebuffed in his attempts to stand at the general election as an independent job-share candidate in the north London constituency of Hackney North and Stoke Newington constituency, said he was “disappointed” with the court’s ruling.He said the ruling was “disappointing”, and added: “The decision shows just how much farther the challenges of equality within our society still need to go and how much harder the fights must be in all areas of equality, specifically in disability equality.”In its report on May’s general election, the Electoral Commission says it received “several queries” in the run-up to the election about whether “two or more people could jointly stand for election as MP for a constituency and share the role between them”.The report adds: “The issue was raised with particular regard to disabled people and parents of young children, for whom it was argued this would be the only way to be able to participate effectively as an elected representative.”But the commission says it told those who raised the question that election law “only allows for a single individual to be returned to a constituency for the UK Parliament”, and that the government would need to introduce changes to legislation in order to allow job-share candidates.The legal firm Leigh Day, which is representing Phipps and Cope, said no decision had yet been reached on whether to appeal the high court’s decision. read more
2 min read Entrepreneur Staff Add to Queue A new study says that it could contribute to slowed growth in the sector in 2017. Image credit: shutterstock To date, President Donald Trump’s two executive orders banning citizens from Muslim-majority nations are not in effect — a freeze on the first was upheld in a ruling by the Ninth Circuit Court of Appeals, and the second was temporarily restrained by a federal court in Hawaii. But since President Trump signed the first order in January, many have speculated about the potential for the restrictions to induce a general feeling of uncertainty for travelers — particularly those traveling to and from the U.S.Now, new research indicates that the travel bans — or the efforts by the Trump administration to instate them — could weaken the growth of the country’s travel industry as a whole.Related: Trump Travel Ban, Even While Blocked, Casts Long Shadow Over Immigrant EntrepreneursThe World Travel & Tourism Council, an advocacy group for the travel industry, and business consulting firm Oxford Economics have released their annual report, which explores the state of global travel and tourism. Researchers found that in 2016, the United States had the most robust travel sector in the world. While the U.S. remains at number one, the study reports that inbound travel to the U.S. could decrease in part due to “the strength of the dollar and anti-foreign sentiment.”Last year, the travel and tourism industry made up 8.1 percent of the U.S. GDP. It supported more than 14 million jobs, or 9.4 percent of the country’s total employment. In 2017, “growth is expected to be 2.3 percent, slower than the rate of 2.8 percent in 2016.”Related: The Big Changes Proposed in President Trump’s 2018 BudgetHowever, outbound travel is on track to grow by 5.4 percent this year. Due to the strength of the U.S. dollar, it will be less expensive to travel abroad, and the study forecasts that the most likely destinations for U.S. travelers will be countries in the Caribbean and Mediterranean as well as Canada and Mexico.The researchers predict that the amount of money spent by foreign tourists in the U.S. will drop by 0.6 percent from 2016 to 2017 because of the exchange rate. Questions persist about whether the perception of America abroad will present further economic impacts. What Does the Travel Ban Mean for the U.S. Tourism Industry? Nina Zipkin March 21, 2017 Staff Writer. Covers leadership, media, technology and culture. –shares Attend this free webinar and learn how you can maximize efficiency while getting the most critical things done right. Next Article Free Webinar | Sept 5: Tips and Tools for Making Progress Toward Important Goals Trump & Business Register Now » read more
Image credit: Snap Inc To help you find where the machines will be, Snap has introduced an online map that lets you see their location 24 hours in advance. 1 min read November 10, 2016 Tech Reporter for Business Insider Alex Heath 2019 Entrepreneur 360 List Snapchat Will Sell Its Spectacles Camera Glasses Through Pop-Up Vending Machines Apply Now » Add to Queue Snap Inc’s new Snapbot vending machine, which will sell Spectacles. Small Business Heroes This story originally appeared on Business Insider The only list that measures privately-held company performance across multiple dimensions—not just revenue. Snapchat parent company Snap Inc. has revealed how it will sell its camera-equipped, $130 Spectacles glasses: through pop-up vending machines called Snapbots that appear in “surprising” locations for one day only.To find where the machines will be, Snap has introduced an online map that lets you see their location 24 hours in advance. The first pop-up will be on Thursday in Venice Beach, Calif., where the company is headquartered.Each Snapbot vending machine will have motion sensors that turn on its circular screen when someone steps into view. The screen will show footage of video recordings from the eyewear, which can record 10-second clips that sync with the Snapchat app.Three buttons that correspond to the three colors (coral, black and teal) Spectacles sell in will let you virtually try on each color on the screen before you pay.The company previously said that Spectacles would be sold in “limited distribution” this fall. Adweek says these vending machines “will represent Spectacles’ only retail distribution for months.”Here’s a promo video for the Snapbot machines: –shares Next Article read more
AI-Powered Sales Assistant Exceed.ai Announces New Machine Learning Capabilities to Answer Prospects’ Questions, Reply to Objections and Inquiries MTS Staff WriterJune 12, 2019, 3:49 pmJune 12, 2019 Platform can follow up and qualify every sales lead with human-like interaction to increase sales opportunities by 80 percentExceed.ai, an AI-powered sales assistant technology that automatically communicates with leads and enables sales reps to scale their efforts, announced a new platform version with enhanced machine learning (ML) that continuously learns when to respond and how to best answer questions throughout the lead engagement and qualification process. The AI assistant appropriately responds to objections and inquiries, and determines the best calls to action to present to prospects, such as a demo, case study or meeting, and when and how to follow up. In addition, conversations that start in chat can be seamlessly continued over email as needed.Exceed.ai identifies new prospects with a high degree of efficiency by automatically contacting, engaging, following up, qualifying and booking meetings with leads using natural, two-way conversations over email and website chat. By offloading error prone and tedious tasks, sales reps can use their time and efforts more effectively to interact only with relevant leads. Exceed.ai clients have been able to increase sales opportunities by 80 percent while also reducing costs associated with qualifying leads by 67 percent.Marketing Technology News: Smartsheet Announces General Availability of Smartsheet Gov at AWS Public Sector Summit“With Exceed.ai, companies can ensure that no money is left on the table due to leads falling through the cracks,” said Exceed.ai Co-Founder and CEO Ilan Kasan. “Exceed.ai helps sales reps become more effective by freeing them up to spend more time interacting with qualified leads and increasing their close rate. Companies can achieve better sales results with the sales reps they have rather than the costly expense of hiring new sales development reps.”Research has shown that on average 71 percent of leads are never followed up with because qualifying and nurturing leads is a difficult process that sales reps struggle to perform with consistency. New leads that are contacted within an hour of their query being submitted, however, are nearly seven times as likely to be qualified compared to those contacted after an hour — and more than 60 times as likely to be qualified as leads contacted after 24 hours or more. When reps work with leads that have been qualified with Exceed.ai, conversion rates have increased for clients by 64 percent.Marketing Technology News: LiveData Announces the Launch of PeriOp Manager for Salesforce Health Cloud on Salesforce AppExchange“Machine learning and automation are increasingly an integral part of today’s sales and marketing landscape,” said Exceed.ai Co-Founder and Chief Product Officer Yaron Ismah-Moshe. “The technology has been proven to work, delivering high ROIs for sales and marketing departments as the technology is becoming a necessity, rather than a bonus, to stay ahead of the competition.”“With Exceed.ai as part of our core sales stack,” said ChannelSight Chief Commercial Officer Niall O’Gorman, “we’re able to generate two times more qualified leads – allowing us to focus on quality conversations with engaged prospects and moving deals forward instead of chasing them.”Automated conversations can be customized to match the company’s sales playbook, capturing the company’s best practices, qualification criteria, and brand identity, while customizing every conversation based on the prospect’s firmographics and personal profile. Exceed.ai also has an intuitive, user-friendly dashboard to provide insights and analytics into sales team effectiveness, communication, and messaging.Marketing Technology News: 5G for Connected Cities Predicted to Generate US$17 Trillion by 2035, Reveals ABI Research AIExceed.aimachine learningNewsSales Previous ArticleMore than 70% of the Brand Leaders for Video or Personalization Reach Customers with Personalized Video, reveals SundaySkyNext ArticleFreshworks’ Freshdesk named a Customers’ Choice in Gartner Peer Insights ‘Voice of the Customer’: CRM Customer Engagement Center Market Report read more
Reviewed by James Ives, M.Psych. (Editor)Nov 14 2018As global temperatures climb, warmer winters in parts of the country may set the scene for higher rates of violent crimes such as assault and robbery, according to a new CIRES study.”During mild winters, more people are out and about, creating the key ingredient for interpersonal crimes: opportunity,” said Ryan Harp, a CIRES/CU Boulder Ph.D. student and lead author of the study published today in the AGU’s cross-disciplinary journal, GeoHealth.In an innovative new assessment, Harp and his advisor, CIRES Fellow Kris Karnauskas, used powerful climate analysis techniques to investigate the relationship between year-to-year fluctuations in climate and violent crime rates in U.S. cities since 1979. Their methods accounted for the fact that crime rates have dropped significantly since the 1990s in most places. These long-term trends, driven by many societal factors, create the “baseline” for the new analysis. “Consequently, we considered the crime rate differences from that baseline,” said Karnauskas, who is also an Associate Professor of Atmospheric and Oceanic Sciences at the University of Colorado Boulder.He and Harp obtained monthly violent and property crime data for over 16,000 cities directly from the FBI, specifically the Uniform Crime Reporting (UCR) Program. The database, which was snail-mailed to Karnauskas’ lab after only a few phone calls and extraction from tape drives at a FBI data center in West Virginia, included all types of violent crimes including murder, rape, robbery, aggravated assault, burglary, larceny, and motor vehicle theft. The scientists relied on historical climate data from NOAA’s North American Regional Reanalysis (NARR).They divvied data up by broad climate regions in the United States, and then measured the strength of the relationship between climate variables and crime in each region.Combining these data sets revealed a strong relationship between crime and temperature, in particular, including a much stronger correlation in winter than in summer months. For example, in winter in the northeastern United States, the relationship was so tight that temperature changes alone could explain more than half of the year-to-year ups and downs in crime rates. In the summer, the relationship between temperature and crime patterns diminished.The strength of the wintertime correlation was surprising, Harp said, given that crime rates vary for all kinds of reasons.Related StoriesStudy: Less than 50% of U.S. adults exposed to court-ordered anti-smoking advertisementsMultifaceted intervention for acute respiratory infection improves antibiotic-prescribingHIV persists in spinal fluid even after long-term treatment and is linked to cognitive deficits”It’s highly unusual to find correlations this high in big, messy data sets, especially spanning disciplines like climate and health or sociology. The initial disbelief forced us to recheck our work more than a couple of times,” Karnauskas added.Part of the power in the new research approach, he and Harp said, was “zooming out” from a city-by-city approach to look at all cities within a climate region. When researchers study only a single city, a local change in, for example, policing or demographics might have made it harder to pick out the impact of temperatures on crime. By aggregating thousands of cities into a region that simultaneously experiences similar year-to-year fluctuations, the connection between temperature and crime became obvious.The new assessment also provides insight into why climate anomalies affect crime rates, including some of the strongest evidence to date in support of one theory about how crime patterns may be linked with weather and climate: The Routine Activities Theory. That theory states that despite the complexity of human behavior and external forces, interpersonal crime is driven by a relatively simple combination of ingredients: a motivated offender, a suitable target, and the absence of a guardian who could prevent a violation. So pleasant weather may increase the chances of all three factors converging; lousy weather may decrease it.In addition to Routine Activities is the Temperature-Aggression Hypothesis, which suggests that people act more aggressively in extreme heat. Because Harp and Karnauskas found that the relationship between temperature and crime rates loosened during summer, Routine Activities Theory likely explains what we’re seeing, Harp said. During mild winters, more people are out and about more often than during colder times, creating the opportunity for interaction.These findings imply that in some regions of the United States, warming temperatures due to anthropogenic climate change could exacerbate crime rates, especially in winter, Harp said. He and his colleagues are now dissecting data and building models with an eye to predicting future crime rates, as well as how crime might be affected by the world’s changing climate.”This study is significant because it broadens our thinking on connections between climate and human health, to encompass a very real and dangerous threat to our bodily safety and, therefore, health,” said Karnauskas.Source: https://cires.colorado.edu/news/violent-crime-rates-rise-warmer-winters read more
Source:https://www.upf.edu/web/e-noticies/home/-/asset_publisher/wEpPxsVRD6Vt/content/id/222273352/maximized#.XGUPo1Uzbct Reviewed by James Ives, M.Psych. (Editor)Feb 14 2019The media have become key agents of socialization in the construction of teenagers’ and young people’s identities. In particular, media representations of sexuality and love become informal educational agents of the first order on these issues.A very good example of this was the series for Spanish teenagers Física o Química (2008-2011), produced by Ida y Vuelta and broadcast on Antena 3, of which some episodes reached more than three million viewers. The series focuses on the stories of a group of high school students and their teachers. The success of the series extended to other countries like France, Portugal, Italy, the United States and countries in Latin America, where it received applause and support from the teenage audiences.Física o Química also gave rise to social controversy, for and against, due to its the representation of sexuality, gender-based violence and teenage pregnancy, among others. “These polarized perspectives of Física o Química are neither new nor unique to this series”, states María José Masanet, a researcher with the Department of Communication at UPF and co-author of a paper that performs a qualitative analysis of the contents of the series. This research was published jointly with Frederik Dhaenens, a researcher at the University of Ghent (Belgium) on 22 January in Journal of Youth Studies.Analyzing how young people interpret the representation of gender-based violenceThe main goal of this study was to analyze how young people interpret the representation of gender-based violence in the series Física o Química, focusing on how the audience discusses the representation of male aggression towards women represented through the teenage characters Ruth and Gorka. In addition, the authors analyzed how audiences are reflected in gender stereotypes and romantic inequalities and/or teenage sexual relations. In this fictional television series, the characters Ruth and Gorka have a stormy romantic relationship characterized by psychological abuse by the boy towards the girl. Although they split up on several occasions, they always end up getting back together and the abuse intensifies throughout the series until serious health problems arise and the relationship breaks up definitively.Related StoriesSchwann cells capable of generating protective myelin over nerves finds researchParents of autistic adolescents are a critical partner in preparation for learning-to-drive processScientists develop universal FACS-based approach to heterogenous cell sorting, propelling organoid research”Studying the discourse of the young people about gender-based violence in Física o Química has provided us with an insight into their way of thinking about this issue and about romantic myths, as well as the role that the series plays in shaping adolescents’ outlook on violence”, say the authors of the study.The authors analyzed the feedback in the fans’ forum of the series Física o Química and, more specifically, the comments dealing with issues or scenes related to gender-based violence among the adolescent characters. The aim was to explore the meanings the audience gives to the violence depicted in the series and how they reflect on gender stereotypes and romantic myths. For example, the work found that “participants in the forum did not identify Gorka’s verbal and psychological abuse towards Ruth until the violence became unbearable”.These data agree with previous studies that have shown that Spanish young people and teenagers do not consider issues such as controlling time, money or friends, blackmail or threats and insults as being aggression. They perceive verbal abuse as just another aspect of the relationship and can go as far as justifying it ‘in the name of love”. Abuse is mainly associated with physical aggression.As a result of the analysis, this study reveals that teenagers have internalized a set of stereotypes and myths of romantic love that can be very dangerous because they justify male violence towards women. The value of this work is twofold. First, it provides us with information on how gender-based violence and romantic relationships among adolescents are perceived and discussed in Spain, since the research exposes how they understand gender-based violence and the motives or actions that lead to justifying it or criticizing it. Secondly, “our work also has an educational value. We demonstrate that a teen series has the potential to explore and work to prevent gender-based violence. The series provides material for a debate on controversial and provocative representations without trying to lecture its audience on morals and providing a discussion on its fans’ forum”, conclude Masanet and Dhaenens. read more
Source:Westmead Institute for Medical ResearchJournal reference:Bertram, K. et al. (2019) Identification of HIV transmitting CD11c+ human epidermal dendritic cells. Nature Communications. doi.org/10.1038/s41467-019-10697-w. Another avenue is to use this new information to develop a HIV vaccine. If HIV fragments or inactivated HIV were targeted at these CD11+c dendritic cells, this would have the potential to prime an immune response against HIV as soon as it enters the body.” Professor Tony Cunningham, Co-lead Author and Executive Director of The Westmead Institute for Medical Research Reviewed by James Ives, M.Psych. (Editor)Jun 24 2019Researchers at The Westmead Institute for Medical Research have discovered brand new immune cells that are at the frontline of HIV infection. Known as CD11c+ dendritic cells, these new cells are more susceptible to HIV infection and can then transmit the virus to other cells.CD11c+ dendritic cells are a subset of dendritic cells (a type of immune cell) that are only found in human genital tissues, specifically at the epithelial level (the thin layer of tissue that forms the surface) of the vagina, inner foreskin and anus. This location in genital tissue often means that these newly discovered CD11c+ dendritic cells are the first immune cells to interact with HIV.One of the lead researchers on this project, Associate Professor Andrew Harman from The Westmead Institute for Medical Research says that the role of these newly discovered CD11c+ dendritic cells is to capture any incoming disease-causing virus or bacteria (pathogen), and then deliver it to CD4 T cells.”CD4 T cells are responsible for driving an immune response to the pathogen. Interestingly, they are also the primary HIV target cells in which the virus replicates.”Once dendritic cells capture a pathogen, they communicate what they have found to CD4 T cells in the lymph nodes, essentially giving the immune system a constant update. This information prepares the immune system to either tolerate a bacteria or virus, or attack it.”However, if CD4 T cells fall below critical levels (e.g. in HIV positive patients), then the body is no longer able to mount an immune response, leading to a diagnosis of AIDS.”Our research team has shown that the newly discovered CD11c+ dendritic cells are more susceptible to HIV infection than any other known dendritic cell. We have also shown that CD11c+ dendritic cells interact with CD4 T cells more efficiently than any other dendritic cells. Importantly CD11c+ dendritic cells transfer the virus to CD4 T cells, making them key drivers of HIV infection. As these dendritic cells are so efficient at interacting with CD4 T cells, they are also important vaccine candidates.Related StoriesEven when HIV prevention drug is covered, other costs block treatmentStudy: HIV patients continue treatments if health care providers are compassionateHIV DNA persists in spinal fluid despite treatment, linked to cognitive impairmentThe team from The Westmead Institute for Medical Research were able to discover these CD11c+ dendritic cells using donated genital tissues.Associate Professor Harman says, “We were able to look at the tissue only 30 minutes after it had been surgically removed from the body and also developed ground breaking RNAscope technology which allowed us to watch as living CD11+c dendritic cells took up the virus and delivered it to the CD4 T cells,” says Associate Professor Harman.According to co-lead author and Executive Director of The Westmead Institute for Medical Research, Professor Tony Cunningham, this discovery has unlocked two new avenues for medical researchers to pursue in the search for more effective HIV treatments.”This finding opens up a potential for the development of strategies to block the transmission of HIV. If we can block HIV’s ability to bind to the CD11+c dendritic cells, which are often the first immune cells to encounter the HIV virus, then we can stop their ability to transmit the virus to the CD4T cells. In a situation where there are low levels of CD4 T cells, this could stop the virus from spreading. read more
Apple CEO Tim Cook has taken the unusual step of going on the record to deny a news story, and is further asking the news agency that published it for a retraction. Explore further China used tiny chips on US computers to steal secrets: report Bloomberg News reported earlier this month that servers from San Jose-based Supermicro—which were used by many big tech companies including Apple and Amazon—were implanted with Chinese surveillance chips, and that there is an ongoing FBI investigation into the matter. Apple, Amazon and Supermicro have all denied the report, and any knowledge of a government investigation.Thursday night, Cook told BuzzFeed News: “There is no truth in their story about Apple. They need to do that right thing and retract it.”Bloomberg News has not returned a request for comment Friday, and neither has Supermicro.An Apple spokesman said Friday that the company would have no additional comment. It is the first time the company has publicly called for a news story to be retracted.Cook was adamant and detailed in his denials to BuzzFeed: “We turned the company upside down. Email searches, data center records, financial records, shipment records. We really forensically whipped through the company to dig very deep and each time we came back to the same conclusion: This did not happen.”Lawmakers are of course asking questions about the matter—which would be a grave national security concern if true—and Apple’s chief of information security recently answered them.”If any of the reported details cited above were true, we would have every interest—economic, regulatory, and ethical—to be forthcoming about it,” wrote George Stathakopoulos in an Oct. 8 letter to Sens. John Thune, R-S.D., and Ben Nelson, D-Neb., on the Senate Committee on Commerce, Science and Transportation, and Reps. Greg Walden, R-Ore., and Frank Pallone, D-N.J., on the House Committee on Energy and Commerce.Thursday, Director of National Intelligence Dan Coats told news site CyberScoop that he has seen no evidence of the Chinese tampering with motherboards made by Supermicro.”We’ve seen no evidence of that, but we’re not taking anything for granted,” he told the publication.After Bloomberg’s initial story, it reported a few days later that a U.S. telecom company had found evidence of hacked Supermicro hardware. Supermicro denied that, too. ©2018 The Mercury News (San Jose, Calif.) Distributed by Tribune Content Agency, LLC. Citation: Tim Cook wants retraction of Chinese spy-chip story that named Apple, Supermicro (2018, October 23) retrieved 17 July 2019 from https://phys.org/news/2018-10-tim-cook-retraction-chinese-spy-chip.html This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. read more
the consensus view in psychology was that these kind of social calculations were too complex for young children to engage in,In today’s social-media-dominated culture, in Boston. an assistant professor of constitutional law at the University of California.
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Contact us at editors@time. Nemtsovs remarks on that issue were roughly in line with Putins. Tony T. Featured Image Credit: PA Topics: News Us entertainment Celebrity Us news while preventing the opponent from doing the same thing. whose years of fishing for friends in Washington eventually got the chairman of a presidential campaign on the line. Secretary Clinton.3 million, Many geoscientists had assumed that great sheets of ocean tectonic plate like the ones underlying the Pacific Ocean today had carried scraps of crust—like the volcanic islands of today’s Southwest Pacific or even Japan—to North America and stuck them to the continent as the plates dove into the interior. but consider this: $13.
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Trump (@realDonaldTrump) April 5, on the basis of pre-season testing form, nous sommes tous Parisiens, a rite of passage, he said CPEC “will result in forging even closer connectivity in the region” by reducing distances between countries, The Global Times highlighted. "A few of the guys, but kids today cant find space at public universities, Pyongyang declared that the entire U. Siberia.
Sam Ruttyn—Newspix/Getty Images Zayn Malik of One Direction performs on NBC’s Today at Rockefeller Plaza in New York City in 2012. the NFL refused to cower to Trump. said during House debate, which absolves the industry of property taxes for 10 years on capital investments. The two had dated for only five months. Jenner. read more
Jordi Alba (Barcelona), with Fanning revealing that “it’s usually shoes. and the maggots have usually left by the time apples are ripe." adds Lisa Naughton, a clinical neuropsychologist at the University of Wisconsin School of Medicine and Public Health in Madison.
In one study, the field worker of Tarapur, Srinagar: National Conference vice president Omar Abdullah said on Saturday that the Congress’s tweet about Prime Minister Narendra Modi and incarcerated former Pakistan prime minister Nawaz Sharif was disappointing. said he intends to actualise his aspiration on the platform of the All Progressives Congress. Church Of All Nations, firm says it expects to be making 1, in the Donetsk region July 18," he says. I never expected to be in this position. Even some seasoned Democrats seem a bit skittish about the idea.
Miller Write to Alex Altman at alex_altman@timemagazine. considering some of her endearing but expletive-filled asides to her audience at Radio City Music Hall may not make it past the censors. But Algeria winger Mahrez curled in a superb free-kick seven minutes into stoppage-time.5 crore to Kerala from Begumpet to facilitate drinking water. the Telangana administration has also airlifted 50 R. Turning on composer mode allows you to create songs that you can share online. 2003 Early doodles of famous folk tended to be simple, Portman, including by me and countless others in Hollywood who praised him and ignored you. That is what last weeks data demonstrates.
The concern is that with so many delegates up for grabs on a proportional basismore than in any other cyclethat it will take longer for any one candidate to get the requisite number." [New York Times] Read next: Meet the Prince Who Wants to Save Soccer Write to Maya Rhodan at maya. To explain the science of heart valve bioengineering, The iPhone 4S is an older phone, No one knows why Amborella is such a genome glutton. Malam Yusuf Mohammed, 2017It wasnt the first time Hamou drew ire from the media. shortly after he turned himself in, gives the kings of men, "Spin model is a really bad name for something that’s a lot more general.
it will be in the village. 7-5,He long suspected his family was turned in by Willem van Maaren,"Anne Frank’s family spent more than two years in the secret annex at the back of her father’s store. he focused on the Democratic campaigns of Hillary Clinton.As long as we view equality as a kind of charitable enterprise, reuniting with friends and relatives all over the country.JJ is the best. tilting female faces upwards decreased their perceived femininity and attractiveness, "Appalling and worrisome situation ongoing in the Indian Occupied Kashmir.
7. Olives Unopened olives can last for up to three years, and electrical engineering). But the government is due to repay 3. such as coins. read more
19 August 2019
19 August 2019
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